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The relationship between osteoporosis and diabetes: exploring the bone-metabolism interface

The relationship between osteoporosis and diabetes: exploring the bone-metabolism interface
骨质疏松症与糖尿病的关系:探索骨代谢界面
批准号:
nhmrc : 1133521
负责人:
金额:
$5.7万
依托单位国家:
澳大利亚
项目类别:
Postgraduate Scholarships
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2020-12-31

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中文摘要
翻译
骨质疏松症和糖尿病是影响许多澳大利亚人的两种常见疾病。糖尿病患者骨折风险增加,然而这种增加骨折风险的潜在机制尚不清楚。我们假设,由于胰岛素水平升高(如在2型糖尿病中看到的),骨骼重塑发生了变化,并将探索导致骨折风险增加的因素,并检查治疗如何降低骨折发生率。
英文摘要
Osteoporosis and diabetes are two common conditions that affect many Australians. Diabetes patients have an increased risk of fractures, however the underlying mechanisms for this increased fracture risk is unknown. We hypothesise that there are changes in the bone remodelling as a result of increased insulin levels (as seen in type 2 diabetes) and will explore the factors that contribute to the increased fracture risk and examine how treatments can reduce fracture rates.
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