Research Fellowship

研究奖学金

• 批准号: nhmrc : 1022618
• 负责人: Prof Peter Colman
• 金额: $ 55.8万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/research-fellowship/110199
• 关键词: Research; Fellowship

Detailed images of protein molecules underpin our understanding of biological function and our attempts to find new medicines to counter biological malfunction. Proteins belonging to the so-called Bcl-2 family determine whether a cell lives or dies and, because failure to die on cue is a hallmark of many cancers, high resolution images of these molecules will reveal new targets for cancer therapies.

蛋白质分子的详细图像支撑了我们对生物功能的理解以及我们寻找新药来对抗生物功能障碍的尝试。属于所谓的Bcl-2家族的蛋白质决定了细胞的生存或死亡，由于未能及时死亡是许多癌症的标志，这些分子的高分辨率图像将揭示癌症治疗的新靶点。