Role of androgens in polycystic ovary syndrome

多囊卵巢综合征(PCOS)影响着全世界5%-10%的女性，但其起源尚不清楚。雄激素与多囊卵巢综合征的发生有关，但需要决定性的侵入性研究来证实和阐明它们在女性中的作用是不可行的。因此，使用我们创新的雄激素抵抗雌性小鼠模型，这项研究将确定雄激素在多囊卵巢综合征中的作用，旨在更好地了解并找到治疗这种常见女性生殖疾病的新方法。

Polycystic ovary syndrome (PCOS) affects 5-10% of women worldwide, yet its origins remain unknown. Androgens are implicated in the development of PCOS, but the decisive, invasive studies needed to confirm and elucidate their roles are not feasible in women. Hence, using our innovative mouse models of androgen resistant female mice, this study will determine the role of androgens in PCOS aiming to better understand, and identify new treatments for this common female reproductive disorder.