The role of FHL proteins in the pathology of muscular dystrophies: identification of novel therapeutic targets

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Scientists at Monash University have recently identified a protein called FHL1 which promotes skeletal muscle repair-growth and may reverse the muscle degeneration seen in inherited muscular dystrophies. This study will investigate whether FHL1 expression can improve muscle mass in mouse models of muscular dystropy. In doing so, this research improve out understanding of the molecular processes that cause muscular dystrophies and thereby lead the way to new therapies for this family of diseases.