The role of gastric vagal afferents in the food intake reducing effect of oestradiol

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Regulation of food intake is paramount for maintaining health. Nerves from the stomach serve as important regulators of food intake. These nerves can be modulated by chemical substances; however the importance of this modulation is not well defined. The sex steroid, oestradiol, has potent food intake reducing effects, but the mechanism for this is poorly understood. Thus, this fellowship will examine the role that oestradiol has in regulating food intake by acting on nerves within the stomach.