The role of glycaemic variability in influenza virus pathogenesis and immunity

糖尿病患者面临严重流感感染的风险。然而，驱动这种易感性的机制还不完全清楚。这个项目将调查糖尿病患者的血糖水平变化是否会增加流感的严重性，并通过导致氧化应激来损害免疫反应。通过这样做，这个项目的目的是确定减少氧化应激是否会降低糖尿病患者的流感严重程度。

People with diabetes are at risk of severe flu infections. However, the mechanisms that drive this susceptibility are incompletely understood. This project will investigate whether variable blood sugar levels in patients with diabetes increase the severity of the flu and impair the immune response by causing oxidative stress. In doing so, this project aims to identify if reducing oxidative stress will reduce the severity of the flu in patients with diabetes.