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Role of IL-3 in allergic inflammation: modulation of basophils, mast cells, eosinophils and remodelling in asthma.

Role of IL-3 in allergic inflammation: modulation of basophils, mast cells, eosinophils and remodelling in asthma.
IL-3 在过敏性炎症中的作用:调节嗜碱性粒细胞、肥大细胞、嗜酸性粒细胞和哮喘重塑。
批准号:
nhmrc : 471481
负责人:
Prof Ian Young
金额:
$33.03万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31

项目摘要

项目成果

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中文摘要
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英文摘要
Asthma is an important disease in the Australian community. We will investigate how the underlying inflammation in this disease is controlled and will focus our studies on a hormone-like regulator of the immune system called interleukin-3. Our hypothesis is that interleukin-3 regulates basophils, mast cells and remodelling of the airways which are central features of asthma. This study will give a better understanding of how the inflammation is caused and information for new drug targets.
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The Spectral Evolution of Ocean Swell
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Predicting environmental extremes in a period of climate change
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Global trends in oceanic wind speed and wave height
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    DP130100215
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    Discovery Projects
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    2013
  • 负责人:
    Prof Ian Young
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Targeting miRNA to inhibit leukocyte differentiation: a novel anti-inflammatory approach for the treatment of asthma
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    nhmrc : 1026410
  • 项目类别:
    Project Grants
  • 资助金额:
    $40.1万
  • 财政年份:
    2012
  • 负责人:
    Prof Ian Young
  • 依托单位:
国内基金
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  • 资助金额:
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    2026
  • 负责人:
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基于“Akkermansia muciniphila—ILC3/IL-22轴”探究竹节参总皂苷改善高脂饮食诱导的脂质代谢紊乱
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    JCZRLH202600409
  • 项目类别:
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    2026
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草鱼NF-κB p50与IL-10启动子的结合特性及其调控效应