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The role of somatic mutations in CCCTC-binding factor (CTCF) binding sites in cancer

The role of somatic mutations in CCCTC-binding factor (CTCF) binding sites in cancer
CCCTC 结合因子 (CTCF) 结合位点体细胞突变在癌症中的作用
批准号:
nhmrc : 1119932
负责人:
A/Pr Jason Wong
金额:
$25.32万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2019-12-31

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中文摘要
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英文摘要
The three dimensional organisation of genomic DNA has been recognised to play a crucial role in maintaining the stability and function of human cells. In cancer this organisation is often perturbed as a result of mutations to proteins that govern this process. This project will examine how mutations in the DNA may potentially alter the three dimensional organisation of cancer genomes and will identify links between these mutations with cancer development and patient prognosis.
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Investigating the Molecular Basis for Drug Resistance and Disease Relapse in Myelodysplastic Syndromes
  • 批准号:
    nhmrc : GNT1139787
  • 项目类别:
    Project Grants
  • 资助金额:
    $72.26万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Jason Wong
  • 依托单位:
Mutational processes and their impact in cancer genomes
  • 批准号:
    nhmrc : GNT1144204
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $47.67万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Jason Wong
  • 依托单位:
Investigating the Molecular Basis for Drug Resistance and Disease Relapse in Myelodysplastic Syndromes
  • 批准号:
    nhmrc : 1139787
  • 项目类别:
    Project Grants
  • 资助金额:
    $48.85万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Jason Wong
  • 依托单位:
The role of somatic mutations in CCCTC-binding factor (CTCF) binding sites in cancer
  • 批准号:
    nhmrc : GNT1119932
  • 项目类别:
    Project Grants
  • 资助金额:
    $37.11万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Jason Wong
  • 依托单位:
国内基金
海外基金
原生动物四膜虫生殖小核(germline nucleus)体功能(somatic function)的分子基础研究