Investigating the Molecular Basis for Drug Resistance and Disease Relapse in Myelodysplastic Syndromes
Investigating the Molecular Basis for Drug Resistance and Disease Relapse in Myelodysplastic Syndromes
批准号:
nhmrc : GNT1139787
负责人:
A/Pr Jason Wong
金额:
$72.26万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Myelodysplastic Syndromes (MDS) are a group of blood stem cell disorders that result in low blood counts and leukemia especially in the elderly. Azacitidine (AZA) is a drug that improves blood counts and delays progression to leukemia and is the treatment of choice. However, only half the patients treated with AZA ever respond and half of the responders relapse within a year. We will describe the origins of MDS and the basis for drug response, resistance and disease relapse.
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Mutational processes and their impact in cancer genomes
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批准号:nhmrc : GNT1144204
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项目类别:Career Development Fellowships
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资助金额:$47.67万
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财政年份:2018
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负责人:A/Pr Jason Wong
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依托单位:
Investigating the Molecular Basis for Drug Resistance and Disease Relapse in Myelodysplastic Syndromes
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批准号:nhmrc : 1139787
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项目类别:Project Grants
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依托单位:
The role of somatic mutations in CCCTC-binding factor (CTCF) binding sites in cancer
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批准号:nhmrc : 1119932
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资助金额:$25.32万
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财政年份:2017
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负责人:A/Pr Jason Wong
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依托单位:
The role of somatic mutations in CCCTC-binding factor (CTCF) binding sites in cancer
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批准号:nhmrc : GNT1119932
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项目类别:Project Grants
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资助金额:$37.11万
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财政年份:2017
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依托单位:
Investigating the Transcriptional Circuitry of Normal Human Haematopoietic and Leukaemic Cells
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批准号:nhmrc : 1102589
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项目类别:Project Grants
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资助金额:$47.89万
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财政年份:2016
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负责人:A/Pr Jason Wong
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依托单位:
Investigating the Transcriptional Circuitry of Normal Human Haematopoietic and Leukaemic Cells
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批准号:nhmrc : GNT1102589
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项目类别:Project Grants
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资助金额:$69.88万
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财政年份:2016
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负责人:A/Pr Jason Wong
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Reconstructing Transcriptional Networks in Leukaemic Cells
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批准号:nhmrc : 1042934
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项目类别:Project Grants
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资助金额:$50.68万
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财政年份:2013
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负责人:A/Pr Jason Wong
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依托单位:
国内基金
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