Sequencing Periodontal Bacteria To Determine The Relationship Between Periodontits, Renal And Vascular Function Among Indigenous Australian Adults With Chronic Kidney Disease

对牙周细菌进行测序以确定患有慢性肾病的澳大利亚土著成年人的牙周、肾脏和血管功能之间的关系

• 批准号: nhmrc : 1113098
• 金额: $ 22.61万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/sequencing-periodontal-bacteria-kidney-disease/663237
• 关键词: Sequencing; Periodontal; Bacteria; Determine; Relationship

Almost 20% of Indigenous Australian adults exhibit signs of kidney disease. This study will investigate the relationship between sub-gingival (below the gum) bacteria and both kidney and artery function among Indigenous Australian participants with chronic kidney disease. Using an RCT design, the proposed study will investigate whether changes in sub-gingival bacteria and concentration following conventional treatment of periodontitis align with improvements in renal and vascular function.

近20%的澳大利亚土著成年人表现出肾脏疾病的迹象。本研究将调查患有慢性肾病的澳大利亚土著参与者的牙龈下细菌与肾脏和动脉功能之间的关系。采用随机对照试验设计，该研究将调查牙周炎常规治疗后龈下细菌和浓度的变化是否与肾脏和血管功能的改善相一致。