Serial NT-proBNP Monitoring for Predicting Major Cardiovascular Events in the Dialysis Population

连续 NT-proBNP 监测可预测透析人群的主要心血管事件

• 批准号: nhmrc : 1030584
• 负责人: A/Pr Carmel Hawley
• 金额: $ 19.24万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/serial-nt-probnp-dialysis-population/110764
• 关键词: Serial; NT; proBNP; Monitoring; Predicting

Dialysis patients have a 50-100 fold increased risk of dying from heart disease caused by abnormal heart muscle structure and function. Current tests are unable to accurately identify patients at the highest risk. A test that accurately detects the early stages of heart injury is urgently needed. The aim of our research is to develop a monitoring guide using regular testing of a heart hormone (NT-proBNP) to identify high-risk dialysis patients early allowing treatment before a serious medical complication occurs.

透析患者死于由心肌结构和功能异常引起的心脏病的风险增加了50-100倍。目前的测试无法准确识别风险最高的患者。迫切需要一种准确检测心脏损伤早期阶段的测试。我们研究的目的是开发一个监测指南，使用心脏激素（NT-proBNP）的定期检测，以早期识别高风险透析患者，从而在严重的医疗并发症发生之前进行治疗。