Simultaneous targeting of contraception and sexually transmitted disease

同时针对避孕和性传播疾病

• 批准号: nhmrc : 1066326
• 负责人: Prof Adam Mccluskey
• 金额: $ 45.43万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/simultaneous-targeting-contraception-transmitted-disease/455232
• 关键词: Simultaneous; targeting; contraception; sexually; transmitted

This research will generate a completely novel topical contraceptive agent that becomes activated on contact with semen and will simultaneously protect the user against both unwanted fertility and sexually transmitted disease. A prototype compound has already been developed and patented. This research is aimed at the chemical optimization of this reagent, analysis of its mechanism-of-action and characterization of its anti-microbial activity against chlamydia, gonorrhoea, herpes simplex and HIV

这项研究将产生一种全新的局部避孕药，它在与精液接触时被激活，同时保护使用者免受意外生育和性传播疾病的侵害。一种原型化合物已经开发出来并获得了专利。本研究旨在对该试剂进行化学优化，分析其作用机理，并对其对衣原体、淋病、单纯疱疹和HIV的抑菌活性进行表征