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Effects of cortical arousal changes due to sleepiness, alcohol & coffeine on EEG/ERP measures of performance and brain function

Effects of cortical arousal changes due to sleepiness, alcohol & coffeine on EEG/ERP measures of performance and brain function
困倦、酒精对皮质唤醒变化的影响
批准号:
341576-2008
负责人:
Murphy, Timothy
金额:
$1.09万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31

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中文摘要
翻译
这项研究将检查一些挑战对日常功能的影响,如嗜睡、轻度中毒和对风险的反应。将在睡眠剥夺、饮酒和赌博(危险)情况下评估行为表现和大脑活动。此外,咖啡因,一种常见的反制措施,采取扭转困倦和中毒的影响将被检查。我会在人们摄入足够的酒精之前和之后对他们进行测试,将他们的血液酒精浓度提高到大约。(在许多省份,这是法定驾驶限制的一半)和/或在大约20小时不睡觉之后。我将评估他们在各种任务中的表现,同时收集脑电图数据(大脑皮层电活动)。我还将测试一种常见的对策——咖啡因的有效性(从行为和脑电图的角度)。在我的实验中,参与者会得到大约相当于两杯咖啡的量,然后再进行测试,以确定他们的表现是否有所改善,或者他们的大脑活动是否恢复到正常水平。
英文摘要
This research will examine the effects of several challenges to everyday functioning such as sleepiness, mild intoxication and reaction to risk. Behavioural performance and brain activity will be assessed under conditions of sleep deprivation, alcohol consumption and during a gambling (risky) situtation. In addition, caffeine, a common countermeasure taken to reverse the effects of sleepiness and intoxication will be examined. I will test individuals before and after ingesting enough alcohol to raise their blood alcohol to approximately .04 (half the legal limit to drive in many provinces) and/or after approximately 20 hours of wakefulness. I will assess their performance on a variety of tasks while also collecting EEG data (brain electrocortical activity). I will also test the effectiveness (behaviourally and in terms of EEG) of a common countermeasure, caffeine. The individuals in my experiments will receive the equivalent of approximately 2 cups of coffee before being retested to determine if their performance improves, or their brain activity returns to normal levels.
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会议论文
Tools for assessing shared sensory experience in interacting mice.
  • 批准号:
    RGPIN-2022-03723
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $4.01万
  • 财政年份:
    2022
  • 负责人:
    Murphy, Timothy
  • 依托单位:
Effects of cortical arousal changes due to sleepiness, alcohol & coffeine on EEG/ERP measures of performance and brain function
  • 批准号:
    341576-2008
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.09万
  • 财政年份:
    2009
  • 负责人:
    Murphy, Timothy
  • 依托单位:
国内基金
海外基金
Cortical control of internal state in the insular cortex-claustrum region
Cortical Hem与FoxG1相互作用调控齿状回发育的分子机制研究
  • 批准号:
    31171040
  • 项目类别:
    面上项目
  • 资助金额:
    58.0万元
  • 批准年份:
    2011
  • 负责人:
    赵春杰
  • 依托单位:
损伤和修复过程中皮层神经元钙稳态调控机制研究
  • 批准号:
    30670500
  • 项目类别:
    面上项目
  • 资助金额:
    28.0万元
  • 批准年份:
    2006
  • 负责人:
    柴真
  • 依托单位:
去除corticl hem 对大脑皮层和海马发育的影响
  • 批准号:
    30440090
  • 项目类别:
    专项基金项目
  • 资助金额:
    8.0万元
  • 批准年份:
    2004
  • 负责人:
    赵春杰
  • 依托单位: