Solving the causes of and development of new therapies for ankylosing spondylitis and related diseases

解决强直性脊柱炎及相关疾病的病因并开发新疗法

• 批准号: nhmrc : 1118005
• 负责人: Prof Matthew Brown
• 金额: $ 59.07万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/solving-causes-development-related-diseases/946306
• 关键词: Solving; causes; development; new; therapies

Ankylosing spondylitis (AS) is a highly heritable and common form of arthritis affecting primarily the spine and pelvis, and is the 2nd most common form of arthritis worldwide (~0.55%). In this fellowship I will extend my world-leading program of AS research by increasing understanding of its basic causes through research into its genetic and environmental triggers, and from this develop new treatments for this and related diseases such as psoriasis and inflammatory bowel disease.

强直性脊柱炎（AS）是一种高度遗传和常见的关节炎，主要影响脊柱和骨盆，是全球第二常见的关节炎（约0.55%）。在这个奖学金，我将扩大我的世界领先的AS研究计划，通过研究其遗传和环境触发因素来增加对其基本原因的了解，并从这一点上开发新的治疗方法和相关疾病，如牛皮癣和炎症性肠病。