Electrophysiology suite for extracellular recording in cat visual cortex

用于猫视觉皮层细胞外记录的电生理学套件

• 批准号: 360138-2008
• 负责人: Crowder, Nathan
• 金额: $ 8.26万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=403743
• 关键词: Electrophysiology; suite; extracellular; recording; cat

Although the eyes detect light, it is the brain that does most of the work that allows us to see the world around us. Millions of brain cells, also called neurons, work together to analyze the visual scene that is projected onto the back of the eye. Using precision electronics it is possible to monitor the activity of single neurons in the brain in response to precisely controlled visual stimuli. The present proposal requests funding for equipment that will be used to set up an electrophysiological recording facility. This recording laboratory consists of life support, surgery, electrode manufacture and signal acquisition packages. I will use the equipment to record the extracellular activity of individual neurons in the cat primary visual cortex in response to computer generated visual stimuli. These recordings will provide significant insights into information processing in the early visual cortex. This equipment will help my laboratory attain an international level of sophistication, and provide a rich learning environment for trainee neuroscientists.

虽然眼睛能感知光线，但大脑做了大部分工作，让我们看到周围的世界。数以百万计的脑细胞，也称为神经元，共同分析投射到眼睛后部的视觉场景。利用精密电子学，可以监测大脑中单个神经元对精确控制的视觉刺激的反应。本提案要求为将用于建立电生理记录设施的设备提供资金。该记录实验室包括生命支持、手术、电极制造和信号采集包。我将使用该设备记录猫初级视觉皮层中单个神经元对计算机生成的视觉刺激的细胞外活动。这些记录将为早期视觉皮层的信息处理提供重要的见解。这些设备将帮助我的实验室达到国际先进水平，并为实习的神经科学家提供丰富的学习环境。