A study of treatment discontinuation for chronic hepatitis B patients

慢性乙型肝炎患者停止治疗的研究

• 批准号: nhmrc : GNT1066536
• 负责人: A/Pr Paul Desmond
• 金额: $ 94.2万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/study-treatment-discontinuation-b-patients/1344913
• 关键词: study; treatment; discontinuation; chronic; hepatitis

Guidelines currently recommend lifelong treatment for patients with chronic hepatitis B, with associated cost and risks of drug resistance and side effects. It has recently been suggested that up to 50% of patients may safely and successfully stop drug after long-term treatment. Our project will identify which patients can safely stop treatment, by performing detailed studies of the human immune system and the hepatitis B virus. This will be an important advance for patient care.

目前的指南建议对慢性乙型肝炎患者进行终身治疗，并承担相关费用以及耐药性和副作用的风险。最近有研究表明，高达50%的患者在长期治疗后可以安全、成功地停药。我们的项目将通过对人体免疫系统和乙型肝炎病毒进行详细研究来确定哪些患者可以安全地停止治疗。这将是患者护理的一个重要进步。