Tackling obesity by reducing sugar consumption

通过减少糖的消耗来解决肥胖问题

• 批准号: nhmrc : 1146417
• 负责人: Prof Selena Bartlett
• 金额: $ 38.58万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/tackling-obesity-reducing-sugar-consumption/1320655
• 关键词: Tackling; obesity; reducing; sugar; consumption

The brain plays a major role in the overconsumption of high fat/high sugar foods and this contributes to obesity but it receives little attention when it comes to developing novel treatments. My lab showed that a FDA-approved smoking cessation medication, that is a nicotinic receptor modulator, decreased the overconsumption of sugar. This project aims are to identify which nicotinic receptors and brain circuits are involved in the overconsumption of sucrose to improve treatments for obesity.

大脑在高脂肪/高糖食物的过度消费中起着重要作用，这导致肥胖，但在开发新的治疗方法时，它很少受到关注。我的实验室表明，FDA批准的戒烟药物，这是一种烟碱受体调节剂，减少了糖的过度消耗。该项目旨在确定哪些烟碱受体和大脑回路参与了蔗糖的过度消费，以改善肥胖症的治疗。