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Elucidation of the biosynthesis of 4-hydroxy-2-alkylquinolines by pseudomonas aeruginosa

Elucidation of the biosynthesis of 4-hydroxy-2-alkylquinolines by pseudomonas aeruginosa
铜绿假单胞菌生物合成 4-羟基-2-烷基喹啉的阐明
批准号：
38364-2007
负责人：
Lépine, François
金额：
$2.19万
依托单位：
Institut national de la recherche scientifique
依托单位国家：
加拿大
项目类别：
Discovery Grants Program - Individual
财政年份：
2009
资助国家：
加拿大
项目状态：
已结题
起止时间：
2009-01-01 至 2010-12-31
来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=421126
关键词：
Elucidationbiosynthesishydroxyalkylquinolinespseudomonas

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中文摘要
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英文摘要
In recent years it has been demonstrated that bacteria communicate with one another, in a process called « Quorum Sensing ». In this mechanism, bacteria secrete one or many signalling molecules which, when they have reched a specific concentration in the medium, bind to their corresponding regulator protein that will increase the production of the signalling compounds and will also activate other virulence genes. During the early stage of an infection, the advantage of such synchronized behaviour is to wait until the number of bacteria is sufficiently large so that the simultaneous release of virulence factor could overwhelm the host defence.
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A new look at the biosynthesis of 4-hydroxy-2-alkylquinolines in Pseudomonas aeruginosa
A new look at the biosynthesis of 4-hydroxy-2-alkylquinolines in Pseudomonas aeruginosa
A new look at the biosynthesis of 4-hydroxy-2-alkylquinolines in Pseudomonas aeruginosa
A new look at the biosynthesis of 4-hydroxy-2-alkylquinolines in Pseudomonas aeruginosa
国内基金
海外基金
中老年男性迟发性性腺功能障碍（LOH）分子生物学机制的研究
  • 批准号：
    30772285
  • 项目类别：
    面上项目
  • 资助金额：
    30.0万元
  • 批准年份：
    2007
  • 负责人：
    辛钟成
  • 依托单位：
    北京大学