Thalamic neuroplasticity and pain following spinal cord injury

丘脑神经可塑性和脊髓损伤后的疼痛

• 批准号: nhmrc : 1002354
• 负责人: A/Pr Luke Henderson
• 金额: $ 19.97万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/thalamic-neuroplasticity-pain-cord-injury/108807
• 关键词: Thalamic; neuroplasticity; pain; following; spinal

Pain is a major problem for people with spinal cord injuries and is common, severe and difficult to treat. There is increasing evidence to suggest that pain may be linked to specific changes in some brain regions following a spinal cord injury. Several possible brain changes have been suggested but not investigated fully and have different implications for treatment. This project aims to characterise these brain changes with the purpose of developing novel effective and targeted treatments.

疼痛是脊髓损伤患者的主要问题，并且是常见的，严重的和难以治疗的。越来越多的证据表明疼痛可能与脊髓损伤后某些大脑区域的特定变化有关。已经提出了几种可能的大脑变化，但没有充分研究，并且对治疗有不同的影响。该项目旨在研究这些大脑变化，以开发新的有效和有针对性的治疗方法。