Does a pain-specific pathway exist in humans?

人类是否存在疼痛特异性途径？

• 批准号: nhmrc : 1059181
• 负责人: A/Pr Luke Henderson
• 金额: $ 28.74万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/does-pain-specific-exist-humans/454740
• 关键词: Does; pain; specific; pathway; exist

Pain has a detrimental impact on ones quality of life and a significant financial impact on the community. Although some of the pathways that code pain in the brain have been defined, it was recently proposed that there also exists a pain-specific pathway in humans. Using human brain imaging, we aim to determine if such a pathway exists and if it is altered in subjects with chronic pain. The existence of such a pathway would significantly aid in the development of better treatment regimes.

疼痛对一个人的生活质量有不利的影响，对社会的经济影响也很大。虽然在大脑中编码疼痛的一些通路已经被定义，但最近有人提出，在人类中也存在一种疼痛特有的通路。利用人脑成像，我们的目标是确定这种途径是否存在，以及在患有慢性疼痛的受试者中是否发生了变化。这种途径的存在将大大有助于制定更好的治疗制度。