The cellular basis of synaptic integration and modulation in human pyramidal neurons

人锥体神经元突触整合和调节的细胞基础

• 批准号: nhmrc : 2003114
• 金额: $ 91.74万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/the-cellular-basis-pyramidal-neurons/1780062
• 关键词: cellular; basis; synaptic; integration; modulation

Little is known about how human neurons integrate information, and how this process is altered during neuromodulation and disease. This project will address this fundamental gap in knowledge and will for the first time directly examine the neuromodulation of human neurons, and how this important process is altered in brain cancer. Our team of researchers and surgeons in Melbourne and Berlin will be able to provide valuable, and otherwise unattainable, information about the human brain.

关于人类神经元如何整合信息，以及这一过程在神经调节和疾病过程中如何改变，人们知之甚少。该项目将解决这一基本知识差距，并将首次直接研究人类神经元的神经调节，以及这一重要过程在脑癌中是如何改变的。我们在墨尔本和柏林的研究人员和外科医生团队将能够提供有价值的，否则无法获得的关于人类大脑的信息。