The role of host proteases in modulating enteric infectious disease

宿主蛋白酶在调节肠道传染病中的作用

• 批准号: nhmrc : 2002156
• 金额: $ 126.72万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/the-role-host-infectious-disease/1779861
• 关键词: role; host; proteases; modulating; enteric

Bacterial pathogens that cause gut diseases result in 2.5 million deaths per year. The gut is a complex environment consisting of numerous factors that must be balanced to maintain enteric health. When these factors are unbalanced, disease can occur, and infections can cause imbalances. This project will increase our understanding of the role that host proteins play in gut infections, providing knowledge critical for developing improved strategies for disease treatment and prevention.

导致肠道疾病的细菌病原体每年导致250万人死亡。肠道是一个复杂的环境，由许多因素组成，必须保持平衡才能维持肠道健康。当这些因素不平衡时，可能会发生疾病，感染可能会导致失衡。这个项目将增加我们对宿主蛋白在肠道感染中所起作用的理解，为制定改进的疾病治疗和预防策略提供至关重要的知识。