Therapeutic potential of hookworm secreted molecules for the treatment of human autoimmune diseases

钩虫分泌分子治疗人类自身免疫性疾病的治疗潜力

• 批准号: nhmrc : 1052938
• 负责人: Dr Cinzia Cantacessi
• 金额: $ 6.24万
• 依托单位: James Cook University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/therapeutic-potential-hookworm-autoimmune-diseases/112303
• 关键词: Therapeutic; potential; hookworm; secreted; molecules

In developed countries, the increased incidence of allergic and autoimmune diseases has been related to the decreased prevalence of parasitic infections. The present research will explore the role that parasite molecules play in mechanisms that regulate the immune response of their vertebrate hosts and test their potential to become novel therapeutics for the treatment of inflammatory diseases.

在发达国家，过敏性和自身免疫性疾病发病率的增加与寄生虫感染流行率的下降有关。目前的研究将探索寄生虫分子在调节脊椎动物宿主免疫反应的机制中发挥的作用，并测试它们成为治疗炎症性疾病的新型疗法的潜力。