Linking environmental contamination, immunotixicity tests and disease resistance iin birds

将环境污染、免疫毒性测试和鸟类抗病性联系起来

• 批准号: 222876-2009
• 负责人: Smits, Judit
• 金额: $ 1.75万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=425013
• 关键词: Linking; environmental; contamination; immunotixicity; tests

There is deep scientific concern and growing public awareness of human impacts on ecosystem health. Environmental contamination poses threats, perceived and real, to vertebrates inhabiting disturbed areas, with wild birds making up appealing, visible components of the ecosystem. Before they can fly, young birds reflect the quality of air and food in their immediate surroundings, and, as neonates, they are particularly sensitive to food- and air- borne contaminants. A valuable method that scientists have to study the subtle health effects of contaminant exposure is through testing the immune system which is essential for survival in the wild. Many scientists have shown that environmental pollutants do have negative effects on the immune system. This finding has been assumed to mean that those animals are more vulnerable to infectious diseases. However, there are several factors that have not been thoroughly addressed; 1) how to ensure that the immune function tests, mainly developed in domestic poultry, are effective in the wild species on which they are used, and 2) how these mmunological tests relates to disease.

人们对人类对生态系统健康的影响有着深刻的科学关注和日益增长的公众意识。 环境污染对居住在受干扰地区的脊椎动物构成了感知和现实的威胁，而野生鸟类是生态系统中有吸引力的、可见的组成部分。在飞翔之前，幼鸟会反映周围环境的空气和食物质量，并且作为新生儿，它们对食物和空气中的污染物特别敏感。科学家们研究污染物暴露对健康的微妙影响的一个有价值的方法是测试免疫系统，这对于野外生存至关重要。许多科学家已经证明，环境污染物确实会对免疫系统产生负面影响。 这一发现被认为意味着这些动物更容易感染传染病。然而，有几个因素尚未得到彻底解决； 1) 如何确保主要在家禽中开发的免疫功能测试对所使用的野生物种有效，以及 2) 这些免疫学测试与疾病有何关系。