Topical drug delivery based on porous silicon nanoneedles

目前有许多新药只能通过皮下注射针通过皮肤给药，这种方法成本高昂，具有侵入性，并有感染传播的风险。该项目建议开发一种替代策略，该策略基于覆盖着数百万微孔针头的皮肤贴片。这些针头能够无痛地刺穿皮肤，为治疗黑色素瘤或牛皮癣等皮肤病提供快速和微创的给药。

There are currently a number of new drugs that can only be administered through the skin via hypodermic needles, which is costly, invasive and carries the risk of infection spread. This project proposes to develop an alternative strategy based on skin patches covered in millions of microscopic porous needles. These needles are able to puncture the skin painlessly to provide rapid and minimally-invasive administration of drugs for treatment of skin diseases, such as melanoma or psoriasis.