Transcriptome landscape of brown/beige adipogenesis in humans

身体里有三种脂肪：白色、棕色和米色。过量的白色脂肪会导致肥胖，而棕色脂肪则会导致消瘦，并降低血糖水平。最近的动物实验表明，在一定条件下，白色脂肪可以转化为米色脂肪，从而带来减肥等益处。目前的项目资助包括检查在实验室中生长的人类脂肪细胞，以及调查棕色和米色脂肪的遗传学。

There are three kinds of fat in the body: white, brown and beige. While excess white fat results in obesity, brown fat is associated with leanness and lowers blood glucose levels. Recent animal experiments show that under certain conditions, white fat can be transformed into beige fat, leading to benefits such as weight loss. The current project grant involves examination of human fat cells grown in the laboratory and investigation on the genetics of brown and beige fat.