Thyroid-sympathoadrenal regulation of human brown fat

人类棕色脂肪的甲状腺交感肾上腺调节

• 批准号: nhmrc : 1035997
• 负责人: Dr Paul Lee
• 金额: $ 29.82万
• 依托单位: Garvan Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/thyroid-sympathoadrenal-regulation-brown-fat/110995
• 关键词: Thyroid; sympathoadrenal; regulation; human; brown

This project aims to determine how hormones influence the growth and activity of brown fat in humans. Majority of fat cells in the body are white fat cells, which store fat, and cause obesity when in excess. Brown fat cells function like generators. They burn fat and release energy as heat. Humans with lots of brown fat are lean. What controls brown fat activity is currently unknown in humans. This project investigates how hormones influence brown fat activity and may shed light on the therapeutic potential of brown fat in obesity treatment.

该项目旨在确定激素如何影响人类棕色脂肪的生长和活动。身体中的大多数脂肪细胞是白色脂肪细胞，它们储存脂肪，过量时会导致肥胖。棕色脂肪细胞的功能就像发电机一样。它们燃烧脂肪，以热量的形式释放能量。拥有大量棕色脂肪的人是苗条的。目前人类尚不清楚是什么控制了棕色脂肪的活动。该项目调查激素如何影响棕色脂肪的活性，并可能阐明棕色脂肪在肥胖治疗中的治疗潜力。