Structural nanomechanics of self-assembled protein filaments

自组装蛋白丝的结构纳米力学

• 批准号: 355291-2008
• 负责人: Kreplak, Laurent
• 金额: $ 2.22万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=431511
• 关键词: Structural; nanomechanics; self; assembled; protein

Over the last few years, I have been excited by a group of proteins, ubiquitously present in the human body and other mammals that can self-assemble into ultrathin filaments. These "intermediate filaments" are responsible for the unique mechanical properties of some of our tissues, like the upper layer of the skin and our hairs. They are also important structural elements of each of our cells.

在过去的几年里，我对一组蛋白质感到兴奋，这些蛋白质普遍存在于人体和其他哺乳动物体内，它们可以自我组装成超薄的细丝。这些“中间细丝”负责我们一些组织的独特机械性能，比如皮肤的上层和头发。它们也是我们每个细胞的重要结构元素。