Tyrosine Kinase Signalling Networks In Pancreatic Cancer: Relevance To Therapeutic Response And Biomarker Development

胰腺癌中的酪氨酸激酶信号网络：与治疗反应和生物标志物开发的相关性

• 批准号: nhmrc : 1083896
• 负责人: Dr Marina Pajic
• 金额: $ 52.67万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/tyrosine-kinase-signalling-biomarker-development/518962
• 关键词: Tyrosine; Kinase; Signalling; Networks; Pancreatic

Pancreatic cancer is a devastating disease characterized by a lack of effective treatments and biomarkers that identify the best way to treat individual patients. By identifying a novel basis for pancreatic cancer subclassification using cutting edge techniques, we aim to identify therapeutic strategies that can be directed to pancreatic cancer patients in a subgroup-selective manner to ultimately lead to reductions in the morbidity and mortality associated with this devastating disease.

胰腺癌是一种毁灭性疾病，其特点是缺乏有效的治疗方法和生物标志物来确定治疗个体患者的最佳方法。通过使用尖端技术确定胰腺癌亚分类的新基础，我们的目标是确定可以以亚组选择性方式针对胰腺癌患者的治疗策略，最终降低与这种破坏性疾病相关的发病率和死亡率。