Understanding the brain in the transition from acute to chronic low back pain

了解从急性腰痛到慢性腰痛转变过程中的大脑

• 批准号: nhmrc : GNT1094434
• 负责人: Mr WeiJu Chang
• 金额: $ 10.54万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-brain-transition-low-pain/1345948
• 关键词: Understanding; brain; transition; acute; chronic

A critical question in treating low back pain (LBP) is why some people get better after hurting their back while others do not. Physiological mechanisms, such as brain plasticity and central sensitisation, are believed to underpin the transition to persistent pain. This is the first study to evaluate these mechanisms longitudinally and their relationship with LBP outcomes. The result of this research will provide better understanding of pain mechanisms of LBP and assist to develop novel therapy.

治疗腰痛（LBP）的一个关键问题是为什么有些人在背部受伤后会好转，而其他人则不会。生理机制，如大脑可塑性和中枢敏感化，被认为是持续性疼痛的基础。这是第一项纵向评估这些机制及其与LBP结局关系的研究。本研究的结果将有助于更好地了解腰痛的疼痛机制，并有助于开发新的治疗方法。