Laser diode thermal desorption-APCI interface

我们寻求获得一种激光二极管热解吸(LDTD)界面，我们已经成功地使用该界面绕过了用于分析许多新兴有机污染物的液相色谱。这种方法允许分析物直接挥发到电离室(APCI)中，并在串联质谱仪中进行定量，样品周转率低于30秒。这种方法可以节省大量资源，但也有一定的局限性，主要是LDTD方法适用的分析物数量有限，检测限性能较低。到目前为止，我们已经将其应用于水中一些药物、类固醇激素和对羟基苯甲酸酯的分析，但对于污染土壤、水生沉积物和污水污泥等固体物质，我们也取得了很好的结果。我们还改进了这个LDTD接口，以分析空气中的挥发性有机化合物，因此我们能够使用它在线监测BTEX(苯、甲苯、乙苯和二甲苯)和挥发性甲基硅氧烷。

We seek to acquire a laser diode thermal desorption (LDTD) interface that we have successfully used to bypass liquid chromatography for the analysis of many emerging organic contaminants. This method allows the volatilization of analytes directly into an ionization chamber (APCI) and quantification in a tandem mass spectrometer with a sample turnover below 30 sec. That approach permits some large resources savings, but has certain limitations, mainly a somewhat restricted number of analytes amenable to the LDTD method and lower performance for detection limits. We have so far adapted it to the analysis of some pharmaceuticals, steroid hormones and parabens in water, but we also have excellent results with solids such as contaminated soils, aquatic sediments and sewage sludge. We have also modified this LDTD interface to analyze volatile organic compounds in air, we have thus been able to use it for the online monitoring of BTEX (benzene, toluene, ethylbenzene and xylenes) and volatile methylsiloxanes.