Using modelling to evaluate STI epidemiology control strategies and investigate chlamydial within-host disease

使用模型评估性传播感染流行病学控制策略并研究宿主内衣原体疾病

• 批准号: nhmrc : 568705
• 负责人: Dr Davidp Wilson
• 金额: $ 6.28万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/using-modelling-evaluate-host-disease/116083
• 关键词: Using; modelling; evaluate; STI; epidemiology

This research will further our understanding of the mechanisms that give rise to the development of Chlamydia within a cell and how it causes disease, ultimately providing targets for drug-vaccine design. This project will also design and evaluate epidemic control strategies to inform policy makers for reducing the incidence and prevalence of sexually transmitted infections. These applications are addressed by developing mathematical models, biophysical theory, and statistical analyses.

这项研究将进一步了解衣原体在细胞内发育的机制以及它如何引起疾病，最终为药物疫苗设计提供目标。该项目还将设计和评估流行病控制策略，为政策制定者提供减少性传播感染的发病率和流行率的信息。这些应用是通过开发数学模型、生物物理理论和统计分析来解决的。