Using ‘omics to unravel the pathophysiology and repurpose drugs to treat ME/CFS

肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）的病因尚不清楚，但可能涉及产生能量的细胞成分（线粒体）的功能改变。我们将使用最先进的干细胞技术来详细研究这一点，并产生重要的新知识，可以确定治疗ME/CFS的新靶点。我们还将使用一种复杂的技术来筛选药物库，以确定那些可能对ME/CFS治疗有用的药物。

The cause(s) of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are not well known, but may involve altered function by the component of the cell that produces energy (mitochondria). We will use cutting edge stem cell technology to investigate this in detail and generate vital new knowledge that could identify new targets for the treatment of ME/CFS. We will also use a complex technology to screen a library of drugs to identify those that may be useful in the treatment of ME/CFS.