Validation and Effect of Low Endothelial Shear Stress on Coronary Atherosclerosis

低内皮剪切应力对冠状动脉粥样硬化的验证和作用

• 批准号: nhmrc : GNT1161089
• 负责人: Dr Adam Brown
• 金额: $ 19.36万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/validation-effect-low-coronary-atherosclerosis/1349334
• 关键词: Validation; Effect; Low; Endothelial; Shear

Heart disease remains a major concern despite advances in health promotion and treatment options. A major challenge faced by cardiologists is identifying patients that are at highest risk of disease progression or heart attacks. This proposal involves collaboration between cardiologists and engineers, aiming to assess whether mechanical stress induced by blood flow can be reliably calculated from heart scans and if this can be used clinically to improve prediction of clinical events.

尽管在健康促进和治疗选择方面取得了进展，但心脏病仍然是一个主要问题。心脏病专家面临的一个主要挑战是确定疾病进展或心脏病发作风险最高的患者。该提案涉及心脏病专家和工程师之间的合作，旨在评估是否可以从心脏扫描中可靠地计算血流引起的机械应力，以及是否可以在临床上用于改善临床事件的预测。