VITAL: Vaccine immunomodulation throughout the aging lifespan

VITAL：整个衰老过程中的疫苗免疫调节

• 批准号: nhmrc : 1141840
• 负责人: A/Pr Katie Flanagan
• 金额: $ 53.76万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/vital-vaccine-immunomodulation-aging-lifespan/1319566
• 关键词: VITAL; Vaccine; immunomodulation; throughout; aging

The elderly respond less well to vaccines than their younger counterparts. Flu is particularly dangerous to the elderly. In this proposal we will determine the likely immune mechanism undelying this difference, as well as specifically address the urgent issue of whether prior injection with a whooping cough vaccine makes Flu vaccines less likely to be effective.

老年人对疫苗的反应不如年轻人。流感对老年人尤其危险。在本提案中，我们将确定这种差异下可能的免疫机制，并具体解决预先注射百日咳疫苗是否会降低流感疫苗有效性的紧迫问题。