Bicomponent dendritic macromolecules: design and assembly of multifunctional nanomaterials

双组分树枝状大分子：多功能纳米材料的设计与组装

• 批准号: 155460-2008
• 负责人: Kakkar, Ashok
• 金额: $ 2.55万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=452071
• 关键词: Bicomponent; dendritic; macromolecules; design; assembly

This proposal aims at constructing well defined macromolecular heterostructures, and explores their potential in performing multiple predetermined functions, cooperatively and efficiently. These platforms that can provide a synergistic combination of individual and characteristic functionalities, makes them of relevance in a variety of areas including sensors, recognition/delivery vehicles and catalysis. The key to simplicity with which a library of these compositionally diverse dendrimers will be delivered, is the chemoselectivity of amino-stannanes towards acetylenes. Starting from a central core with two distinct focal groups, it will allow efficient build-up of one arm using aminosilanes, followed by second shell hierarchy outward using aminostannanes. The versatility of the approach offers the potential to introduce a variety of dendron structures with a tailored combination of backbones for desired functions. A detailed understanding of the self-organization of these diblock dendrimers that will be investigated extensively in solution and at interfaces, will provide a facile access to novel assemblies with regions of localized functional density. Dendrimers developed in this proposal will be used to fabricate a variety of size and shape controlled metallic nanoparticles. The spatially defined multimetallic systems that will be assembled using bifunctional dendrimers, are excellent candidates in designing co-operative catalysts that can carry out multiple organic transformations in a single pot. In addition, we shall explore self-assembly of a block of these dendrimers into discrete shapes, and then employ the second arm to synthesize nanoparticles at the resulting pre-determined positions. This provides a relatively simple supramolecular approach to fabricate morphologically controlled nanostructures which is essential for tailoring their unique behavior. The broader impact of this proposal is to build cumulative knowledge base on multi-component products, which will be extremely useful in assembling a wide variety of nanoscale structures, and will address key issues in chemistry and materials science.

该提案旨在构建明确的大分子异质结构，并探索它们协同高效地执行多种预定功能的潜力。这些平台可以提供单独和特征功能的协同组合，使其在传感器、识别/交付车辆和催化等多个领域具有相关性。传递这些组成多样的树枝状聚合物的文库的简单性的关键是氨基锡烷对乙炔的化学选择性。从具有两个不同焦点基团的中央核心开始，它将允许使用氨基硅烷有效地构建一个臂，然后使用氨基锡烷向外构建第二个壳层次结构。该方法的多功能性提供了引入各种树突结构的潜力，这些树突结构具有针对所需功能定制的主链组合。对这些二嵌段树枝状聚合物的自组织的详细了解将在溶液和界面中进行广泛研究，将为获得具有局部功能密度区域的新型组件提供便利。该提案中开发的树枝状聚合物将用于制造各种尺寸和形状受控的金属纳米粒子。将使用双功能树枝状聚合物组装的空间限定的多金属系统是设计可在单锅中进行多种有机转化的协同催化剂的优秀候选者。此外，我们将探索将这些树枝状聚合物块自组装成离散形状，然后使用第二臂在所得的预定位置合成纳米颗粒。这提供了一种相对简单的超分子方法来制造形态控制的纳米结构，这对于定制其独特的行为至关重要。该提案更广泛的影响是建立多组分产品的累积知识库，这对于组装各种纳米级结构非常有用，并将解决化学和材料科学中的关键问题。