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Zinc as an antimicrobial agent and its effect on the pathogenesis of Group A Streptococcus

Zinc as an antimicrobial agent and its effect on the pathogenesis of Group A Streptococcus
锌作为抗菌剂及其对 A 族链球菌发病机制的影响
批准号:
nhmrc : 1084460
负责人:
Prof Alastair Mcewan
金额:
$23.5万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2017-12-31

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中文摘要
翻译
该提案的重点是A组链球菌(GAS),这是一种估计每年导致60万人死亡的人类病原体。我们已经表明,宿主免疫系统使用锌作为抗菌剂,GAS具有保护机体免受锌过度刺激的过程。
英文摘要
This proposal focuses on Group A Streptococcus (GAS), a human pathogen estimated to cause 600,000 human deaths per year. We have shown that the host immune system uses zinc as an antibacterial agent and that GAS has processes that protect against zinc ove
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The molecular physiology of Streptococcus pneumoniae during sepsis
  • 批准号:
    nhmrc : 569720
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $15.5万
  • 财政年份:
    2009
  • 负责人:
    Prof Alastair Mcewan
  • 依托单位:
Copper and its antibacterial action: an emerging aspect of host defence against bacterial pathogens
  • 批准号:
    nhmrc : 519722
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $30.33万
  • 财政年份:
    2008
  • 负责人:
    Prof Alastair Mcewan
  • 依托单位:
Multi-copper oxidase mediated iron uptake in Ps. aeruginosa and other pathogenic bacteria: mechanism and role in disease
  • 批准号:
    nhmrc : 252885
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $4.9万
  • 财政年份:
    2003
  • 负责人:
    Prof Alastair Mcewan
  • 依托单位:
Virulence and oxidative stress in Streptococcus pneumoniae
  • 批准号:
    nhmrc : 252886
  • 项目类别:
    NHMRC Project Grants
  • 资助金额:
    $7.34万
  • 财政年份:
    2003
  • 负责人:
    Prof Alastair Mcewan
  • 依托单位:
海外基金