Copper and its antibacterial action: an emerging aspect of host defence against bacterial pathogens

该项目将确定铜作为抗菌剂杀死宿主巨噬细胞（白细胞）内沙门氏菌的方式，并确定沙门氏菌如何防御铜依赖性杀伤。它还将确定铜在脓毒症期间杀死肠外病原体中的作用。这些结果将提供可用于管理和控制细胞内和细胞外细菌病原体感染的信息。

This project will determine the way in which copper is used as an antimicrobial agent to kill Salmonella that reside inside the macrophage (white blood cell) of the host and also determine how Salmonella defends against copper-dependent killing. It will also determine the role of copper in the killing of extra-intestinal pathogens during sepsis. These results will provide information that can be used to manage and control infections intracellular and extracellular bacterial pathogens.