Genetics and evolution of pigmentary traits in human populations

人类色素特征的遗传学和进化

• 批准号: 262080-2010
• 负责人: Parra, Esteban
• 金额: $ 1.97万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=456258
• 关键词: Genetics; evolution; pigmentary; traits; human

The remarkable variation observed in skin, hair and iris pigmentation in human populations is due to differences in the amount, type and distribution of the pigment melanin, which is synthesized by specialized cells known as melanocytes. The last decade has witnessed impressive advances in our understanding of the genetics or normal pigmentation variation, but the detailed picture of the genes involved in these traits remains far from complete.

在人群中观察到的皮肤、毛发和虹膜色素沉着的显著变化是由于黑色素的数量、类型和分布的差异，黑色素是由称为黑素细胞的专门细胞合成的。在过去的十年里，我们对遗传学或正常色素变化的理解取得了令人印象深刻的进展，但与这些特征相关的基因的详细信息还远未完成。