Development and characterisation of novel hydrogel systems for drug delivery

用于药物输送的新型水凝胶系统的开发和表征

• 批准号: ARC : LP0220056
• 负责人: Dr Laura Poole-Warren
• 金额: $ 6.76万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/development-characterisation-novel-drug-delivery/69936
• 关键词: Development; characterisation; novel; hydrogel; systems

Development and characterisation of novel hydrogel systems for drug delivery. The aims of this project are to develop and characterise hydrogel formulations for delivery of active agents, such as protein drugs, and to examine the biological responses to drug loaded hydrogels. In many medical and industrial fields, it is advantageous to control the release of active agents. Controlled release can decrease the dose of active that must be administered, sustain a more constant level of the agent in the environment and can localise the agent at the site where it is needed. This project will advance the theoretical knowledge of polymer degradation combined with protein release, will develop controlled release hydrogel technology that can be applied to medical devices and will train a postgraduate student in biomaterials and drug delivery.

新型水凝胶药物输送系统的开发与表征。该项目的目的是开发和制备用于递送活性剂（如蛋白质药物）的水凝胶制剂，并检查对载药水凝胶的生物反应。在许多医学和工业领域中，控制活性剂的释放是有利的。控释可以减少必须施用的活性剂的剂量，在环境中维持更恒定的药剂水平，并且可以将药剂定位在需要的部位。该项目将推进聚合物降解与蛋白质释放相结合的理论知识，将开发可应用于医疗器械的控释水凝胶技术，并将培养生物材料和药物输送方面的研究生。