Hot-melt extrusion of polymers for pharmaceutical and biomedical applications

用于制药和生物医学应用的聚合物热熔挤出

• 批准号: 298344-2010
• 负责人: Huneault, Michel
• 金额: $ 1.68万
• 依托单位: Université de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=456835
• 关键词: Hot; melt; extrusion; polymers; pharmaceutical

The main objective of this program is to develop the full potential of melt-state extrusion/processing for the efficient fabrication of polymeric drug/biochemical controlled delivery systems for use in pharmaceutics or tissue-engineering applications. The main advantages of melt-state processing in the pharmaceutical and biomedical sector are the absence of residual solvents, the outstanding mixing and concentration uniformity, the ability to shape the material in 3D and the high productivity and the scalability to commercial production. Specific objectives of the program will be to:

该计划的主要目标是开发熔融状态挤出/加工的全部潜力，用于制药或组织工程应用中使用的聚合物药物/生化控制输送系统的有效制造。 熔融态加工在制药和生物医学领域的主要优势是没有残留溶剂，出色的混合和浓度均匀性，能够以3D方式塑造材料，以及高生产率和可扩展性。该方案的具体目标是：