Functional endoscopic fournier domain optical coherence tomography and nano-optical systems for integrated biomedical microscopy

用于集成生物医学显微镜的功能性内窥镜傅尼叶域光学相干断层扫描和纳米光学系统

• 批准号: 341637-2007
• 负责人: Sarunic, Marinko
• 金额: $ 1.89万
• 依托单位: Simon Fraser University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=458493
• 关键词: Functional; endoscopic; fournier; domain; optical

Biomedical imaging using light is an exciting area of research for high resolution structural and functional visualization of cells and tissues in vivo. Optical coherence tomography (OCT) provides non-destructive micrometer scale resolution cross sectional images of tissue which are directly comparable to histology. Recently, a significant increase in attainable OCT system sensitivity has been identified by the use of spectrally resolved Fourier domain (FD) detection. In addition to novel system level benefits for functional imaging, FD OCT facilitates high speed scanning while maintaining high image quality.

生物医学成像利用光是一个令人兴奋的研究领域，高分辨率的结构和功能可视化的细胞和组织在体内。光学相干断层扫描（OCT）提供非破坏性微米级分辨率的组织横截面图像，直接与组织学相比较。最近，通过使用光谱分辨傅立叶域（FD）检测，可以显著提高OCT系统的灵敏度。除了功能成像的新系统级优势外，FD OCT还有助于高速扫描，同时保持高图像质量。