Two photon imaging and optoporation or retinal cells
Two photon imaging and optoporation or retinal cells
批准号:
RTI-2018-00960
负责人:
Sarunic, Marinko
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
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英文摘要
Pharmacological treatments are available for wet Age-related Macular Degeneration (AMD), a leading cause of blindness. In contrast, there is currently no effective treatment for many other irreversible vision robbing diseases, such as dry AMD and glaucoma. The delivery of therapeutic agents to the afflicted cells of the retina is hampered by their location at the back of the eye. In order to get treatments to the retina, the protective features of the eye must be overcome. Nanoparticles are versatile vehicles for delivery of therapeutics to the retina, but often have low uptake in the desired cell layers.
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会议论文
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