Two photon imaging and optoporation or retinal cells
Two photon imaging and optoporation or retinal cells
批准号:
RTI-2018-00960
负责人:
Sarunic, Marinko
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-01-01 至 2018-12-31
中文摘要
湿性老年性黄斑变性(AMD)是导致失明的主要原因,目前已有药物治疗。相比之下,目前还没有有效的治疗方法来治疗许多其他不可逆转的视力剥夺疾病,如干性AMD和青光眼。由于治疗药物位于眼球后部,治疗药物向视网膜受损细胞的输送受到阻碍。为了对视网膜进行治疗,必须克服眼睛的保护功能。纳米颗粒是将治疗药物输送到视网膜的多功能载体,但通常在所需的细胞层中摄取率较低。
英文摘要
Pharmacological treatments are available for wet Age-related Macular Degeneration (AMD), a leading cause of blindness. In contrast, there is currently no effective treatment for many other irreversible vision robbing diseases, such as dry AMD and glaucoma. The delivery of therapeutic agents to the afflicted cells of the retina is hampered by their location at the back of the eye. In order to get treatments to the retina, the protective features of the eye must be overcome. Nanoparticles are versatile vehicles for delivery of therapeutics to the retina, but often have low uptake in the desired cell layers.
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会议论文
Imaging eyes: ocular diagnostics by adaptive optics
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批准号:RGPIN-2017-05997
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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负责人:Sarunic, Marinko
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依托单位:
Imaging eyes: ocular diagnostics by adaptive optics
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批准号:RGPIN-2017-05997
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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负责人:Sarunic, Marinko
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依托单位:
Imaging eyes: ocular diagnostics by adaptive optics
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批准号:RGPIN-2017-05997
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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负责人:Sarunic, Marinko
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依托单位:
Imaging eyes: ocular diagnostics by adaptive optics
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批准号:RGPIN-2017-05997
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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财政年份:2019
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负责人:Sarunic, Marinko
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依托单位:
Imaging eyes: ocular diagnostics by adaptive optics
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批准号:RGPIN-2017-05997
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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负责人:Sarunic, Marinko
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依托单位:
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资助金额:$14.6万
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财政年份:2017
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负责人:Sarunic, Marinko
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依托单位:
Imaging eyes: ocular diagnostics by adaptive optics
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批准号:RGPIN-2017-05997
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.42万
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财政年份:2017
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负责人:Sarunic, Marinko
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依托单位:
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批准号:341637-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.53万
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负责人:Sarunic, Marinko
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依托单位:
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批准号:RTI-2016-00438
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资助金额:$10.93万
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Real-time quantitative measurement of OCT data using GPGPU
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批准号:485511-2015
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Hyperspectral Scanning Laser Ophthalmoscope for Alzheimer's Disease
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批准号:490991-2015
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资助金额:$1.82万
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负责人:Sarunic, Marinko
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依托单位:
Rapid volumetric and functional imaging using low coherence interferometry
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批准号:341637-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.53万
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Novel Optical Coherence Tomography for non-destructive testing
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批准号:463497-2014
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项目类别:Engage Grants Program
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资助金额:$1.82万
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负责人:Sarunic, Marinko
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依托单位:
Rapid volumetric and functional imaging using low coherence interferometry
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批准号:341637-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.53万
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财政年份:2014
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负责人:Sarunic, Marinko
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依托单位:
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.53万
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Compressive sampling for rapid volumetric OCT acquisition
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财政年份:2013
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负责人:Sarunic, Marinko
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依托单位:
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依托单位:
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批准号:341637-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.53万
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财政年份:2012
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负责人:Sarunic, Marinko
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依托单位:
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项目类别:Discovery Grants Program - Individual
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财政年份:2011
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依托单位:
国内基金
海外基金
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项目类别:面上项目
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批准年份:2011
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依托单位:
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