Biomedical speech processing research

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The proposed research focuses on acoustic studies of motor neuron disorders that yield perturbations on the speech produced depending on the location of the lesion in the peripheral or central nervous system. This investigation is based on clinical evidence of a direct correlation between the location of the neurological lesions and the perturbations observed in the produced speech, which enable the determination of unique acoustic patterns that describe the complaints. The neurological disorders that will be studied include amyotrophic lateral sclerosis, multiple sclerosis and Parkinson disease among other neurological impairments. Diagnostic and a detailed characterization of the acoustic perturbations at very early stages of these disorders are important for rehabilitation, treatment and research.