Discovery Projects - Grant ID: DP210100374

点击翻译按钮获取中文摘要

Metallosupramolecular Cages for Enantioselective Applications. The project aims to explore new synthetic routes to functional supramolecular cages/containers which are able to selectively host small molecules in their interior space, and may provide feedback upon the presence of a guest (i.e. molecular sensing) or catalyse reactions within the enclosed cavity. The project expects to produce chiral cages that are capable of detecting specific enantiomers in solution and act upon them. The expected outcome is a deeper understanding of the structure/property relationship of these novel species and steps towards application. This should provide benefits given the application of solution-based methods for enantioselective sensing/catalysis are of significance in high-value pharmaceutical synthesis.