Discovery Projects - Grant ID: DP210100374

发现项目 - 拨款 ID：DP210100374

• 批准号: ARC : DP210100374
• 负责人: David Turner
• 金额: $ 20.9万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/discovery-projects-grant-id-dp210100374/1782723
• 关键词: Discovery; Projects; Grant; ID; DP210100374

Metallosupramolecular Cages for Enantioselective Applications. The project aims to explore new synthetic routes to functional supramolecular cages/containers which are able to selectively host small molecules in their interior space, and may provide feedback upon the presence of a guest (i.e. molecular sensing) or catalyse reactions within the enclosed cavity. The project expects to produce chiral cages that are capable of detecting specific enantiomers in solution and act upon them. The expected outcome is a deeper understanding of the structure/property relationship of these novel species and steps towards application. This should provide benefits given the application of solution-based methods for enantioselective sensing/catalysis are of significance in high-value pharmaceutical synthesis.

金属超分子笼在对映体选择性中的应用。该项目旨在探索功能性超分子笼/容器的新合成路线，这些笼/容器能够选择性地在其内部空间中容纳小分子，并可以在客人存在时提供反馈（即分子传感）或在封闭的空腔内催化反应。该项目预计将产生手性笼，能够检测溶液中的特定对映体并对其起作用。预期的结果是更深入地了解这些新物种的结构/性质关系和应用步骤。这应该提供益处，因为基于溶液的方法用于对映选择性传感/催化在高价值药物合成中具有重要意义。