Elucidating the machanisms by which control abscisic acid levels in plants

脱落酸（阿坝）是一种植物激素，其调节多种植物过程，包括种子成熟和避免/适应非生物和生物胁迫。因此，阐明内源阿坝水平调控的分子机制是改良种子品质和培育抗逆植物的关键。阿坝的水平是由9-顺式-环氧类胡萝卜素双加氧酶（NCEDs）和阿坝8 '-羟化酶（CYP 707 As）的功能微调的，它们分别是阿坝生物合成的限速酶和催化剂。这些酶定位于特定的细胞类型，并以非细胞自主的方式影响植物的系统反应。因此，从ABA合成细胞到响应细胞的未鉴定的阿坝运输机制对于这种激素的功能也是必不可少的。这项研究计划的重点是确定和功能性地表征每个植物细胞中这种激素水平的调节，并最终揭示植物如何感知和应对不断变化的环境。

Abscisic acid (ABA) is a plant hormone that regulates a variety of plant processes including seed maturation and avoidance/adaptation to abiotic and biotic stresses. Therefore, elucidation of molecular mechanisms that regulate endogenous ABA level is the key to modify seed qualities and to produce stress tolerant plants. The level of ABA is fine-tuned by the functions of 9-cis-epoxycarotenoid dioxygenases (NCEDs) and ABA 8'-hydroxylases (CYP707As), rate-limiting enzymes of ABA biosynthesis and catabolism, respectively. These enzymes are localized in particular cell types and affect plants' systemic responses in a non-cell autonomous manner. Consequently, unidentified ABA transport machineries from ABA-synthesizing cells to responding cells are also essential for the functions of this hormone. The focus of this research proposal is to identify and functionally characterize the regulation of this hormone levels in each plant cell and ultimately to uncover how plants sense and respond to the changing environment.