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Using reconsolidation to understand the structure and molecular underpinning of memory - Steacie Supplement

Using reconsolidation to understand the structure and molecular underpinning of memory - Steacie Supplement
使用重新巩固来理解记忆的结构和分子基础 - Steacie Supplement
批准号：
373515-2009
负责人：
Nader, Karim
金额：
$16.25万
依托单位：
McGill University
依托单位国家：
加拿大
项目类别：
EWR Steacie Fellowships - Supplement
财政年份：
2010
资助国家：
加拿大
项目状态：
已结题
起止时间：
2010-01-01 至 2011-12-31
来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=461808
关键词：
Usingreconsolidationunderstandstructuremolecular

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英文摘要
One of the greatest capacities our brains possess is the ability to store memories that can last a lifetime. Memory consolidation theory posits that new memories initially enter a labile state called short term memory (STM) and through the production of new proteins can be transformed into long term memories (LTM). This process is posited to take place only once for each memory. Recently I have shown that following retrieval, consolidated memories require new proteins synthesis in a brain structure called the amygdala in order for them to persist. In other words, the mechanisms involved in the storage of new memories seem to be recapitulated when old memories are reactivated. This phenomenon is called reconsolidation.
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The Role of PKMzeta in Memory Destabilization and Reconsolidation
  • 批准号：
    RGPIN-2017-05140
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $5.68万
  • 财政年份：
    2021
  • 负责人：
    Nader, Karim
  • 依托单位：
    McGill University
The Role of PKMzeta in Memory Destabilization and Reconsolidation
  • 批准号：
    RGPIN-2017-05140
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.84万
  • 财政年份：
    2020
  • 负责人：
    Nader, Karim
  • 依托单位：
    McGill University
The Role of PKMzeta in Memory Destabilization and Reconsolidation
  • 批准号：
    RGPIN-2017-05140
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.84万
  • 财政年份：
    2019
  • 负责人：
    Nader, Karim
  • 依托单位：
    McGill University
The Role of PKMzeta in Memory Destabilization and Reconsolidation
  • 批准号：
    RGPIN-2017-05140
  • 项目类别：
    Discovery Grants Program - Individual
  • 资助金额：
    $2.84万
  • 财政年份：
    2018
  • 负责人：
    Nader, Karim
  • 依托单位：
    McGill University
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