Distillers dried grains with solubles (DDGS) as a potential source of immunomodulatory and growth promoting activity for poultry

含可溶物的干酒糟 (DDGS) 作为家禽免疫调节和生长促进活性的潜在来源

• 批准号: 380272-2008
• 负责人: Slominski, Bogdan
• 金额: $ 4.23万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=463036
• 关键词: Distillers; dried; grains; solubles; DDGS

It is estimated, that in the near future the ethanol plants in Canada will generate 1.3-1.4 million tonnes of corn and wheat distillers dried grains with solubles (DDGS) destined for animal and poultry feeding per year. In order to derive maximum value from these co-products, their natural advantage as feed ingredients must be presented to the poultry industry. DDGS are co-products of brewer's yeast (Saccharomyces cerevisiae) fermentation which contain significant quantities of components (i.e., ß1,3- and ß1,6-glucans, nucleotides, mannan oligo- or polysaccharides) beneficial for gut development and health, and effective in immune system stimulation. The objective of the proposed research is to investigate the effect of corn- and wheat-based DDGS vs. yeast-derived products of brewing and bakery industries on gastrointestinal tract development, immune system function and growth performance of broiler chickens. Exogenous enzyme can be used to modify and to increase availability of active carbohydrate components upon introduction to the bird's digestive system. Potential synergistic effect of these supplements and the use of enzyme technology will be investigated. The milestones of this research are: 1. To investigate the effect of different carbohydrates and nucleotides derivatives from yeast products on innate and acquired immunity, and 2. To determine the immunomodulating and growth promoting effect of dietary DDGS using the chicken model developed for inducing necrotic enteritis caused by Clostridium perfringens. This research will contribute to our better understanding of the nutritive value of DDGS co-products and will promote the use of corn and wheat DDGS, important Canadian feed resources, effectively in poultry rations.

据估计，在不久的将来，加拿大的乙醇工厂每年将产生130万至140万吨玉米和小麦干酒糟和可溶物（DDGS），用于动物和家禽饲养。为了从这些副产品中获得最大价值，必须向家禽业展示其作为饲料成分的天然优势。DDGS是啤酒酵母（Saccharomyces cerevisiae）发酵的副产物，其含有显著量的组分（即，β 1，3-和β 1，6-葡聚糖、核苷酸、甘露寡糖或多糖），有益于肠道发育和健康，并有效刺激免疫系统。本研究的目的是研究基于玉米和小麦的DDGS与酿酒和烘焙行业的酵母衍生产品对肉鸡胃肠道发育、免疫系统功能和生长性能的影响。外源酶可用于修饰和增加引入禽类消化系统后的活性碳水化合物组分的可用性。这些补充剂的潜在协同效应和酶技术的使用将被调查。本研究的里程碑是：1.研究酵母产品中不同碳水化合物和核苷酸衍生物对天然免疫和获得性免疫的影响。利用产气荚膜梭菌引起的鸡坏死性肠炎模型，研究DDGS对鸡的免疫调节和促生长作用。这项研究将有助于我们更好地了解DDGS副产品的营养价值，并将促进玉米和小麦DDGS，加拿大重要的饲料资源，有效地在家禽日粮中的使用。