Proteins at interfaces and modification of surfaces for biological applications

界面蛋白质和生物应用表面修饰

• 批准号: 3529-2010
• 负责人: Brash, John
• 金额: $ 3.93万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2011
• 资助国家: 加拿大
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=473728
• 关键词: Proteins; interfaces; modification; surfaces; biological

This research is in the area of biomaterials, i.e. materials that are used in contact with a biological system whether it be the human body, a bodily fluid like blood or tears, or any fluid that contains biological components. Our work is focused on biocompatibility and on understanding how proteins and cells interact at the interface between the biomaterial and the biosystem. In addition we exploit our developing understanding of these biointeractions in the design of new materials. The work has two main themes:

这项研究是在生物材料领域，即与生物系统接触使用的材料，无论是人体，血液或眼泪等体液，还是含有生物成分的任何液体。我们的工作重点是生物相容性和了解蛋白质和细胞如何在生物材料和生物系统之间的界面相互作用。此外，我们利用我们对这些生物相互作用的不断发展的理解来设计新材料。这项工作有两个主题：