Attachment of Growth Factors to Pure, Plasma Modified and Coated Titanium Substrates

生长因子与纯、等离子体改性和涂层钛基材的附着

• 批准号: ARC : LP0220842
• 负责人: Dr Michael Conlon
• 金额: $ 6.76万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2002
• 资助国家: 澳大利亚
• 起止时间: 2002-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/attachment-growth-factors-titanium-substrates/63985
• 关键词: Attachment; Growth; Factors; Pure; Plasma

Attachment of Growth Factors to Pure, Plasma Modified and Coated Titanium Substrates. Titanium and its alloys are routinely used as medical and dental implants. Despite coating with hydroxyapatite, a material well known to improve implant fixation, many such implants fail because of lack of strong integration with bone. This proposal aims at achieving long-term stability of titanium implants through their surface modification and subsequent attachment of growth factors. The use of latter has already been shown to help bone-implant integration. Successful project implementation will provide titanium implant surfaces that will help achieve speedier and improved implant fixation with long-term stability. Knowledge, expertise and techniques developed will help the industry partner expanding its research base and business and generating wealth in Australia. Training of world-class research students in the emerging field of biotechnology will be another major outcome.

生长因子在纯钛、等离子体修饰和涂层钛衬底上的附着。钛及其合金通常用作医疗和牙科植入物。尽管涂层了羟基磷灰石，一种众所周知的改善种植体固定的材料，但许多这样的植入物失败了，因为缺乏与骨的紧密结合。这项建议旨在通过钛种植体的表面修饰和随后的生长因子附着来实现钛种植体的长期稳定性。后者的使用已经被证明有助于骨-种植体的结合。成功的项目实施将提供钛植入物表面，有助于实现更快和更好的植入物固定，并具有长期稳定性。开发的知识、专业知识和技术将帮助该行业合作伙伴扩大其研究基础和业务，并在澳大利亚创造财富。培训新兴生物技术领域的世界级研究学生将是另一个主要成果。